SFB 1054

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Publications 2020

Kutukculer, N.*, Seeholzer, T.*, O’Neill, T.J., Graß, C., Aykut, A., Karaca, N.E., Durmaz, A., Cogulu, O., Aksu, G., Gehring, G., Gewies, A., Krappmann D. (2020). Human immune disorder associated with homozygous hypomorphic mutation affecting MALT1B splice variant. D. J Allergy Clin Immunol. accepted. *equal contribution [Project  A04]

Kranich, J., Chlis, N.-K., Rausch, L., Latha, A., Schifferer, M., Kurz, T., Kia, A.F.-A., Simons, M., Theis, F.J., and Brocker, T. (2020). In vivo identification of apoptotic and extracellular vesicle-bound live cells using image-based deep learning. J. Extracell. Vesicles 9, http://doi.org/10.1080/20013078.2020.1792683 [Project B03]

Huber, J.E., Ahlfeld, J., Scheck, M.K., Zaucha, M., Witter, K., Lehmann, L., Karimzadeh, H., Pritsch, M., Hoelscher, M., von Sonnenburg, F., Dick, A., Barba‐Spaeth, G., Krug, A.B., Rothenfußer, S. and Baumjohann, D. (2020). Dynamic changes in circulating T follicular helper cell composition predict neutralising antibody responses after yellow fever vaccination. Clin Transl Immunol, 9: e1129. doi:10.1002/cti2.1129 [Projects A06 and B12]

Matthias, J., Heink, S., Picard, F., Zeiträg, J., Kolz, A., Chao, Y.Y., Soll, D., Almeida, G., Glasmacher, E., Jacobsen, I.D., Riedel, T., Peters, A., Baumjohann, D., Huber, M., Korn, T., and Zielinski, C. (2020). Salt generates anti-inflammatory Th17 cells but amplifies pathogenicity in pro-inflammatory cytokine microenvironments. J. Clin. Invest. (accepted) [Project B06, B10, B12]

Zeiträg, J., Alterauge, D., Dahlström, F., and Baumjohann, D. (2020). Gene Dose Matters: Considerations for the Use of Inducible CD4-CreERT2 Mouse Lines. Eur. J. Immunol. 50, 603-605 doi: 10.1002/eji.201948461. [Project B12]

Schmidt, A., Huber, J.E., Alp, S., Robert, G., Reichel, C.A., Herrmann, M., Keppler, O.T., Leeuw, T., and Baumjohann, D. (2020). Complex human adenoid tissue-based ex vivo culture systems reveal anti- in fl ammatory drug effects on germinal center T and B cells. EbioMedicine. 53, 1–16. doi: 10.1016/j.ebiom.2020.102684. [Project B12]

Huber, J.E., Chang, Y., Meinl, I., Kümpfel, T., Meinl, E., and Baumjohann, D. (2020). Fingolimod Profoundly Reduces Frequencies and Alters Subset Composition of Circulating T Follicular Helper Cells in Multiple Sclerosis Patients. J. Immunol. 204, 1101-1110 doi: 10.4049/jimmunol.1900955 [Project B12]

Jardine, S., Anderson, S., Babcock, S., Leung, G., Pan, J., Dhingani, N., Warner, N., Guo, C., Siddiqui, I., Kotlarz, D., Dowling, J.J., Melnyk, R., Snapper, S.B., Klein, C., Thiagarajah, J.R., and Muise, A.M. (2020). Drug Screen Identifies Leflunomide for Treatment of Inflammatory Bowel Disease Caused by TTC7A Deficiency. Gastroenterology 158, 1000–1015. doi: 10.1053/j.gastro.2019.11.019 [Project A05]

Mufazalov, I.A., Andruszewski, D., Schelmbauer, C., Heink, S., Blanfeld, M., Masri, J., Tang, Y., Schüler, R., Eich, C., Wunderlich, F.T., Karbach, S.H., Bluestone, J.A., Korn, T., and Waisman, A. (2020). Cutting Edge: IL-6–Driven Immune Dysregulation Is Strictly Dependent on IL-6R α-Chain Expression. J. Immunol. 204, 747–751. doi: 10.4049/jimmunol.1900876. [Project B06]

Kretschmer, L., Flossdorf, M., Mir, J., Cho, Y.L., Plambeck, M., Treise, I., Toska, A., Heinzel, S., Schiemann, M., Busch, D.H., and Buchholz, V.R. (2020). Differential expansion of T central memory precursor and effector subsets is regulated by division speed. Nat. Commun. 11. doi: 10.1038/s41467-019-13788-w. [Project B09]

Jansma, M., Linke-Winnebeck, C., Eustermann, S., Lammens, K., Kostrewa, D., Stakyte, K., Litz, C., Kessler, B., and Hopfner, K.P. (2020). Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State. Structure 28, 83-95.e5. doi: 10.1016/j.str.2019.10.013. [Project B02]



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