Publications
Dursun E, Endele M, Musumeci A, Failmezger H, Wang SH, Tresch A, Schroeder T, Krug AB. Continuous single cell imaging reveals sequential steps of plasmacytoid dendritic cell development from common dendritic cell progenitors. Sci Rep. 2016 Nov 28;6:37462. doi: 10.1038/srep37462. [Project A06]
Serr I, Fürst RW, Ott VB, Scherm MG, Nikolaev A, Gökmen F, Kälin S, Zillmer S, Bunk M, Weigmann B, Kunschke N, Loretz B, Lehr CM, Kirchner B, Haase B, Pfaffl M, Waisman A, Willis RA, Ziegler AG, Daniel C. miRNA92a targets KLF2 and the phosphatase PTEN signaling to promote human T follicular helper precursors in T1D islet autoimmunity. Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):E6659-E6668 [Associated Project 02]
Albanese, M.*, Tagawa, T.*, Bouvet, M., Maliqi, L., Lutter, D., Hoser, J., Hastreiter, M., Hayes, M., Sugden, B., Martin, L., Moosmann, A., & Hammerschmidt, W. (2016). Epstein- Barr virus microRNAs reduce immune surveillance by virus-specific CD8+ T cells. Proc Natl Acad Sci U S A. doi:10.1073/pnas.1605884113 (*equal author contribution). [Project B05]
Tagawa, T.*, Albanese, M.*, Bouvet, M., Moosmann, A., Mautner, J., Heissmeyer, V., Zielinski, C., Lutter, D., Hoser, J., Hastreiter, M., Hayes, M., Sugden, B., & Hammerschmidt, W. (2016). Epstein-Barr viral miRNAs inhibit antiviral CD4+ T cell responses targeting IL- 12 and peptide processing. J Exp Med, 213(10), 2065-2080. doi:10.1084/jem.20160248 (*equal author contribution). [Projects B05, A03]
von Rohrscheidt J, Petrozziello E, Nedjic J, Federle C, Krzyzak L, Ploegh HL, Ishido S, Steinkasserer A, Klein L. Thymic CD4 T cell selection requires attenuation of March8-mediated MHCII turnover in cortical epithelial cells through CD83. J Exp Med. 2016 Aug 22;213(9):1685-94. doi: 10.1084/jem.20160316. [Projects A01, IRTG]
Poltorak MP, Zielinski CE. Hierarchical governance of cytokine production by 6-sulfo LacNAc (slan) dendritic cells for the control of psoriasis pathogenesis. Exp Dermatol. 2016 Aug 19. doi: 10.1111/exd.13170. [Project B10]
Maul, J., Baumjohann, D. (2016) Emerging Roles for MicroRNAs in T Follicular Helper Cell Differentiation. Trends Immunol. 2016 May;37(5):297-309. doi: 10.1016/j.it.2016.03.003. [Associated Project 04]
Steinbach K, Vincenti I, Kreutzfeldt M, Page N, Muschaweckh A, Wagner I, Drexler I, Pinschewer D, Korn T, Merkler D. (2016) Brain-resident memory T cells represent an autonomous cytotoxic barrier to viral infection.
J Exp Med, accepted May 2016. [Project B06]
Li Q, Lee CH, Peters LA, Mastropaolo LA, Thoni C, Elkadri A, Schwerd T, Zhu J, Thand B, Zjao Y, Hao K, Dinarzo A, Hoffman G, Kidd BA, Murchie R, Al Adham Z, Guo C, Kotlarz D, Cutz E, Walters TD, Shouval DS, Curran M, Dobrin R, Brodmerkel C, Snapper SB, Klein C, Btumell JH, Hu M, Nanan R, Snanter-Nanan B, Wong M, Le Deist F, Haddad E, Rolfman CM, Deslandres C, Griffiths AM, Gaskin KJ, Uhlig HH, Schadt EE, Muise AM. (2016) Variants in TRIM22 That Affect NOD2 Signaling Are Associated With Very-Early-Onset Inflammatory Bowel Disease. Gastroenterology 2016;150:1196-1207. [Project A05]
Janowski R, Heinz GA, Schlundt A, Wommelsdorf N, Brenner S, Gruber AR, Blank M, Buch T, Buhmann R, Zavolan M, Niessind D, Heissmeyer V, Sattler M. (2016) Roquin recognizes a non-canonial hexaloop structure in the 3-UTR of Ox40. Nat Commun 7, 11032. [Project A03]
Jeltsch KM, Heissmeyer Vigo (2016) Regulation of T cell signaling and autoimmunity by RNA-binding proteins. Curr Opin Immunol 39, 127-135. [Project A03]
Noster R, de Koning HD, Maier E, Prelog M, Lainka E, Zielinski CE. (2016) Dysregulation of proinflammatory versus anti-inflammatory human TH17 cell functionalities in the autoinflammatory Schnitzler syndrome. J Allergy Clin Immunol. 2016 Mar 31. [Project B10]
Brian D. Stadinski, Reinhard Obst, Eric S. Huseby (2016) A 'hotspot' for autoimmune T cells in type 1 diabetes. JCI, Vol 126 (6), June 2016. [Project B07]
Meininger, I, Griesbach RA, Hu D, Gehring, T, Bertossi, A, Kranich, J, Oeckinghaus, A, Eitelhuber, AC, Greczmiel, U, Gewies, A, Schmidt-Supprian, M, Ruland, J, Brocker, T, Heissmeyer, V, Heyd, F, Krappmann, D. (2016) Alternative splicing of MALT1 controls signaling and activation of CD4+ T cells. Nat Commun. 2016 Apr 12;7:11929. [Projects A02, A03, A04, B01, B03]
Halle S, Keyser KA, Stahl FR, Busche A, Marquardt A, Zheng X, Galla M, Heissmeyer V, Heller K, Boelter J, Wagner K, Bischoff Y, Martens R, Braun A, Werth K, Uvarovski A, Kempf H, Meyer-Herrmann M, Arens R, Kremer M, Sutter G, Messerle M, Förster R. (2016) In Vivo Killing Capacity of Cytotoxic T Cells Is Limited and Involves Dynamic Interactions and T Cell Cooperativity. Immunity. 2016 Feb 16;44(2):233-45. [Project A03]
Schlundt A, Niessing D, Heissmeyer V, Sattler M. (2016) RNA recognition by Roquin in posttranscriptional gene regulation. Wiley Interdiscip Rev RNA, 2016 Feb 4. [Project A03]
Pablo Vargas, Paolo Maiuri, Marine Bretou, Pablo J. Sáez, Paolo Pierobo, Mathieu Maurin, Mélanie Chabaud, Danielle Lankar, Dorian Obino, Emmanuel Terriac, Matthew Raab, Hawa-Racine Thiam, Thomas Brocker, Susan M. Kitchen-Goosen, Arthur S. Alberts, Praveen Sunaremi, Xia Sheng, Rong Li, Raphael Voituriez, Matthieu Piel, Ana-Maria Lennon-Duménil. (2015) Innate control of actin nucleation determines distinct migratory behaviors in dendritic cells.
Nat Cell Biol. 2016 Jan;18(1):43-53. [Project B03]
